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Immunoablation does not delay the neurologic progression of X-linked adrenoleukodystrophy
M J Nowaczyk1, E F Saunders, I Tein
1Department of Pediatrics, Hospital for Sick Children, Ontario, Canada.
The Journal of Pediatrics
|November 5, 1997
Abstract:
We report the results of a near total myeloablation in preparation for bone marrow transplantation in a boy with minimal symptoms of X-linked adrenoleukodystrophy. Severe cerebral X-linked adrenoleukodystrophy developed in the patient after failure of bone marrow transplantation. This experience suggests that immunotherapy alone is not responsible for the improvement observed in some patients with X-ALD after BMT.