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Drug-induced disorders

E G Holland1, F V Degruy

  • 1University of South Alabama College of Medicine, Mobile, USA.

American Family Physician
|November 26, 1997
PubMed
Summary
This summary is machine-generated.

Hospital-acquired injuries affect over 1 million patients annually, with drug-induced disorders causing significant harm and costs. Improving clinician awareness and patient assessment can prevent many adverse drug events.

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Area of Science:

  • Clinical Medicine
  • Patient Safety
  • Pharmacology

Background:

  • Over 1 million patients are injured in hospitals yearly, with 180,000 deaths.
  • Drug-related morbidity and mortality cost over $136 billion annually.
  • Most drug-induced disorders are predictable and preventable.

Purpose of the Study:

  • To highlight the incidence and impact of drug-induced disorders in hospitalized patients.
  • To emphasize the role of clinician awareness and patient assessment in preventing adverse drug events.
  • To underscore the importance of comprehensive medication history taking.

Main Methods:

  • Review of estimates on hospital-acquired injuries and drug-related morbidity.
  • Analysis of common causes of adverse drug events, including interactions.

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  • Emphasis on clinician's role in recognizing compromised organ function and drug-induced problems.

    • Main Results:

    • Adverse drug events are frequently linked to drug-drug, drug-disease, or drug-food interactions.
    • Clinician awareness of causative agents and patient organ function is crucial for prevention.
    • Thorough medication history is key to identifying potential drug-induced problems.

    Conclusions:

    • Increased clinician awareness of drug-induced disorders can significantly minimize their incidence.
    • Comprehensive patient assessment, including all substances used, is vital for identifying and preventing drug-induced problems.
    • Preventing adverse drug events through better awareness and assessment improves patient safety and reduces healthcare costs.