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Updated: Aug 18, 2026

Electrophysiological Motor Unit Number Estimation (MUNE) Measuring Compound Muscle Action Potential (CMAP) in Mouse Hindlimb Muscles
Published on: September 25, 2015
Functional state of segmental motoneurons in Wilson-Konovalov hepatocerebral dystrophy
1Department of Neurological Diseases and Neurosurgery, I. P. Pavlov Russian Medical University.
Abstract:
Stimulatory electromyography was used to investigate 12 patients, and chronaximetric investigations were performed in 18. Peak H-potential amplitudes indicated reductions in reflex excitability in the motoneuron pool. The stimulus size required for inducing threshold H-reflexes demonstrated a high level of reflex excitability among those alpha-motoneurons probably involved in generating hyperkinesia. Motor response parameters showed the direct electrical excitability of motor units to be elevated. Changes in H-reflex and M-response parameters demonstrated functional rearrangement of the movement analyzer after stereotaxic surgery. The functional states of the alpha- and gamma-systems are discussed.
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