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Exercise-induced increase in serum creatine kinase is modified by subsequent bed rest
E Havas1, J Komulainen, V Vihko
1LIKES-Research Center, University Campus, Jyväskylä, Finland. havas@maila.jyu.fi
International Journal of Sports Medicine
|January 27, 1998
Summary
Bed rest after strenuous exercise may reduce creatine kinase (CK) levels in the blood. This suggests inactivity impacts enzyme transport and release from muscles, affecting athletic recovery.
Area of Science:
- Exercise Physiology
- Biochemistry
- Sports Medicine
Background:
- Strenuous exercise increases serum creatine kinase (CK) activity.
- Peripheral lymph flow is reduced by bed rest.
- The impact of immediate post-exercise bed rest on CK behavior is not well understood.
Purpose of the Study:
- To investigate the effect of immediate post-exercise bed rest on serum creatine kinase (CK) activity.
- To determine if bed rest influences the later post-exercise CK response and response to repeated exercise.
Main Methods:
- Eleven endurance athletes completed an 18 km run.
- Six athletes underwent 23 hours of bed rest (BR group).
- Five athletes maintained normal activity (Control group, C).
- Both groups performed a 45-min light jog after the bed rest period.
Main Results:
- Serum CK increased threefold in both groups 7 hours post-run.
- CK levels increased by 30% in C but decreased in BR over the next 16 hours.
- Light jogging transiently increased CK in C but not in BR.
Conclusions:
- Post-exercise bed rest may diminish later serum CK responses.
- Short-term physical inactivity might reduce both lymphatic transport and release of CK from muscles.
- Bed rest could potentially affect athletic recovery by altering enzyme kinetics.