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[The effect of Listeria monocytogenes on the blood system]
O A Iurkina1, M R Karpova, V V Novitskiĭ
1Siberian Medical University, Research Institute of Pharmacology, Tomsk, Russia.
Zhurnal Mikrobiologii, Epidemiologii I Immunobiologii
|February 14, 1998
Abstract:
The influence of L. monocytogenes on the hemopoietic system was studied in mouse experiments. All elements of hemopoiesis were damaged. The most pronounced changes developed in erythropoiesis. This was testified by a decrease in erythrocyte count and hemoglobin content in peripheral blood, by the hypoplasia of the hemopoietic erythroid germ in the marrow, as well as by the decrease of yield in culture CFU-E. These changes in the hemopoietic tissue supposedly caused by the direct action of L. monocytogenes and its toxins.