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Updated: Aug 15, 2026

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
Published on: April 4, 2022
Compared contralateral application of topical nitroglycerin on purpura fulminans
J Irazuzta1, J Jarrell, A Portillo
1Division of Critical Care Medicine, Children's Medical Center, Dayton, Ohio, USA.
Abstract:
In cases of purpura fulminans (PF), various treatments have been used to prevent the cutaneous involvement and extensive skin necrosis that can be both disfuguring and debilitating. In this article, we present a case where improvement in the progression of purpuric areas was accomplished by topical administration of nitroglycerin (TNG), as evidenced by comparison with symmetrical contralateral areas not so treated.
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