Mechanism of action of aspartic proteases

[Finding an "invisible" binding site for low-molecular compounds on a protein molecule and predicting their inhibiting activity].

Molekuliarnaia biologiia·2014

[Modeling of substrate and inhibitory complexes of histidine-aspartic protease].

Bioorganicheskaia khimiia·2008

Cloning and molecular modeling of duodenase with respect to evolution of substrate specificity within mammalian serine proteases that have lost a conserved active-site disulfide bond.

Biochemistry. Biokhimiia·2005

[Conserved interactions of the active carboxyls in pepsin-like enzymes and retroviral proteases].

Molekuliarnaia biologiia·2002

[Molecular dynamics analysis of chymosin conformations in solution and in crystalline environment].

Molekuliarnaia biologiia·2002

[A new program complex EFOLD for molecular modeling: the use of a flexible weighting coefficient scheme and the standard valence geometry in modeling the enzyme active sites].

Bioorganicheskaia khimiia·2002

Nucleoskeletal Proteins in Early Embryogenesis.

Advances in experimental medicine and biology·2026

Nuclear Dynamics and Its Timing Regulation Revealed by Live-Cell Imaging.

Advances in experimental medicine and biology·2026

Histone Modifications in Mammalian Early Embryos.

Advances in experimental medicine and biology·2026

Oocyte Kinetochores at the Nexus of Meiotic Drive and Segregation Fidelity.

Advances in experimental medicine and biology·2026

Asymmetric Chromosome Establishment and Segregation During Germline Stem Cell Division.

Advances in experimental medicine and biology·2026

Non-random Sister Chromatid Segregation Mediated by Ribosomal DNA in Drosophila Male Germline Stem Cells.

Advances in experimental medicine and biology·2026

Non-oxidative and selective methanol dehydrogenation to formaldehyde on Cu and Pd/Cu model catalyst surfaces: roles of step sites and deposited Pd.

Physical chemistry chemical physics : PCCP·2026

Nanoscale visualization of plasmon-enhanced hydrogen activation on a Pt(111) surface.

Nature chemistry·2026

Thermally and electronically triggered hydrogen shift within a CHCH2 species via surface-assisted hydrogen tunneling.

Nature communications·2026

Mechanistic Insights Into Luminol Chemiexcitation: The Role of the Amide Carbonyls.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026

The Origin of the Kinetic Isotope Effect and Mechanism of H/D Exchange in Radical C-C Bond Formation Catalyzed by Benzylsuccinate Synthase: Experiments and Microkinetic Modeling.

The journal of physical chemistry. B·2026

The Symmetry Principle in Catalysis: A Viewpoint of the Pseudo-Jahn-Teller Effect.

The journal of physical chemistry letters·2026

Related Experiment Videos

Mechanism of action of aspartic proteases

Related Concept Videos

[Finding an "invisible" binding site for low-molecular compounds on a protein molecule and predicting their inhibiting activity].

[Modeling of substrate and inhibitory complexes of histidine-aspartic protease].

Cloning and molecular modeling of duodenase with respect to evolution of substrate specificity within mammalian serine proteases that have lost a conserved active-site disulfide bond.

[Conserved interactions of the active carboxyls in pepsin-like enzymes and retroviral proteases].

[Molecular dynamics analysis of chymosin conformations in solution and in crystalline environment].

[A new program complex EFOLD for molecular modeling: the use of a flexible weighting coefficient scheme and the standard valence geometry in modeling the enzyme active sites].

Nucleoskeletal Proteins in Early Embryogenesis.

Nuclear Dynamics and Its Timing Regulation Revealed by Live-Cell Imaging.

Histone Modifications in Mammalian Early Embryos.

Oocyte Kinetochores at the Nexus of Meiotic Drive and Segregation Fidelity.

Asymmetric Chromosome Establishment and Segregation During Germline Stem Cell Division.

Non-random Sister Chromatid Segregation Mediated by Ribosomal DNA in Drosophila Male Germline Stem Cells.

Non-oxidative and selective methanol dehydrogenation to formaldehyde on Cu and Pd/Cu model catalyst surfaces: roles of step sites and deposited Pd.

Nanoscale visualization of plasmon-enhanced hydrogen activation on a Pt(111) surface.

Thermally and electronically triggered hydrogen shift within a CHCH2 species via surface-assisted hydrogen tunneling.

Mechanistic Insights Into Luminol Chemiexcitation: The Role of the Amide Carbonyls.

The Origin of the Kinetic Isotope Effect and Mechanism of H/D Exchange in Radical C-C Bond Formation Catalyzed by Benzylsuccinate Synthase: Experiments and Microkinetic Modeling.

The Symmetry Principle in Catalysis: A Viewpoint of the Pseudo-Jahn-Teller Effect.

Related Experiment Videos

Mechanism of action of aspartic proteases

Related Concept Videos

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