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Stereotactic radiosurgery for tentorial meningiomas
N Muthukumar1, D Kondziolka, L D Lunsford
1Department of Neurological Surgery, University of Pittsburgh School of Medicine, PA, USA.
Acta Neurochirurgica
|August 5, 1998
Summary
Gamma Knife stereotactic radiosurgery offers a safe and effective treatment for tentorial meningiomas. This study shows high tumor control rates and clinical improvement in patients, whether used as a primary or adjuvant therapy.
Area of Science:
- Neurosurgery
- Radiation Oncology
Background:
- Tentorial meningiomas are challenging tumors despite advances in microsurgical resection.
- Patients often experience symptoms like headache and trigeminal nerve deficits.
Purpose of the Study:
- To evaluate the efficacy and safety of Gamma Knife stereotactic radiosurgery for tentorial meningiomas.
- To assess clinical outcomes and tumor control rates after radiosurgery.
Main Methods:
- Retrospective analysis of 41 patients with tentorial meningiomas treated with Gamma Knife radiosurgery over 9 years.
- Doses ranged from 24-40 Gy maximum and 12-20 Gy margin.
- Follow-up included clinical evaluation and imaging for an average of 3 years.
Main Results:
- Overall tumor control rate of 98% (18 reduced size, 22 stable, 1 increased).
- 19 patients showed clinical improvement, 20 remained stable.
- No major complications reported, indicating safety.
Conclusions:
- Gamma Knife stereotactic radiosurgery is a safe and effective treatment option for tentorial meningiomas.
- It can be used as a primary or adjuvant therapy, achieving high tumor control and patient benefit.