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[Bacteroides fragilis. Its isolation and antibiotic sensitivity]
Annales De Biologie Clinique
|January 1, 1976
Summary
This study presents a method for identifying anaerobic gram-negative bacteria like Bacteroides fragilis in lab samples. Certain antibiotics, including tetracyclines, clindamycin, and metronidazole, showed significant in vitro activity against these bacteria.
Area of Science:
- Microbiology
- Clinical Bacteriology
Context:
- Bacteroides fragilis is a common anaerobic gram-negative bacterium found in pathological samples.
- Accurate identification of anaerobic bacteria is crucial for effective clinical treatment.
- Routine bacteriological laboratories require efficient methods for bacterial identification.
Purpose:
- To present an identification method for strict anaerobic gram-negative bacteria, specifically Bacteroides fragilis.
- To determine the in vitro antibiotic activity against a selection of 20 Bacteroides strains.
Summary:
- A method for identifying strict anaerobic gram-negative bacteria in pathological samples was developed.
- The study evaluated the mean inhibitory concentration of various antibiotics against 20 Bacteroides strains.
- Two groups of bacteria based on antibiotic activity were identified: low and high in vitro activity.
Impact:
- The developed method is suitable for routine bacteriological laboratories.
- Findings highlight the in vitro efficacy of tetracyclines, clindamycin, and metronidazole against certain Bacteroides strains.
- This research aids in selecting appropriate antibiotic treatments for infections caused by Bacteroides fragilis.