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[Atherogenesis and the acute-phase reaction of the liver]
V A Nagornev1, P G Nazarov, V A Polevshchikov
1Institute of Experimental Medicine, St.-Petersburg.
Arkhiv Patologii
|February 9, 1999
Abstract:
Data from literature are given on the role of "acute phase" proteins in inflammation and their connection with lipoproteins. Intensive production of acute phase proteins is shown to take place in modelling of experimental atherosclerosis. The hypothesis is proposed that allows to consider the acute phase reaction of the liver as a very important condition of modified lipoproteins formation acquiring autoantigenic properties.