Sean P Moran

5PUBLICATIONS
12CO-AUTHORS
Biomolecular modelling and designMolecular targetsCharacterisation of biological macromoleculesMedical devices
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Publications (5)

|Aug 28, 2024
Discovery of VU6007496: Challenges in the Development of an M1 Positive Allosteric Modulator Backup Candidate.

Julie L Engers, Katrina A Bollinger, Rory A Capstick

|Mar 21, 2022
Novel Fluorescence-Based High-Throughput FLIPR Assay Utilizing Membrane-Tethered Genetic Calcium Sensors to Identify T-Type Calcium Channel Modulators.

Yan-Ling Zhang, Sean P Moran, Andrew Allen

|Dec 05, 2019
Biased M1 receptor-positive allosteric modulators reveal role of phospholipase D in M1-dependent rodent cortical plasticity.

Sean P Moran, Zixiu Xiang, Catherine A Doyle

|Apr 28, 2018
A Novel M1 PAM VU0486846 Exerts Efficacy in Cognition Models without Displaying Agonist Activity or Cholinergic Toxicity.

Jerri M Rook, Jeanette L Bertron, Hyekyung P Cho

|Apr 24, 2018
PF-06827443 Displays Robust Allosteric Agonist and Positive Allosteric Modulator Activity in High Receptor Reserve and Native Systems.

Sean P Moran, Hyekyung P Cho, James Maksymetz

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Frequent Collaborators

4 joint publications

Craig W Lindsley

1 joint publications

Kellie D Nance

1 joint publications

Zixiu Xiang

1 joint publications

Catherine A Doyle