Matthew R Hassler

6PUBLICATIONS
31CO-AUTHORS
Biologically active moleculesMolecular targetsNatural language processingMedical molecular engineering of nucleic acids and proteinsGlycoconjugates
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Publications (6)

|Aug 01, 2024
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones.

Ken Yamada, Vignesh N Hariharan, Jillian Caiazzi

|Jul 09, 2024
RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice.

Alexandra Weiss, James W Gilbert, Iris Valeria Rivera Flores

|Feb 13, 2024
A combinatorial approach for achieving CNS-selective RNAi.

Chantal M Ferguson, Bruno M D C Godinho, Dimas Echeverria

|Jul 03, 2023
Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.

Vignesh Narayan Hariharan, Jillian Caiazzi, Rachael Miller

|Aug 04, 2019
A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system.

Julia F Alterman, Bruno M D C Godinho, Matthew R Hassler

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