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Matthew R Hassler

6PUBLICATIONS

31CO-AUTHORS

Biologically active moleculesMolecular targetsNatural language processingMedical molecular engineering of nucleic acids and proteinsGlycoconjugates

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Publications (6)

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|Aug 01, 2024

Enhancing siRNA efficacy in vivo with extended nucleic acid backbones.

Ken Yamada, Vignesh N Hariharan, Jillian Caiazzi

|Jul 09, 2024

RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice.

Alexandra Weiss, James W Gilbert, Iris Valeria Rivera Flores

|Feb 13, 2024

A combinatorial approach for achieving CNS-selective RNAi.

Chantal M Ferguson, Bruno M D C Godinho, Dimas Echeverria

|Jul 03, 2023

Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.

Vignesh Narayan Hariharan, Jillian Caiazzi, Rachael Miller

|Dec 01, 2021

Structurally constrained phosphonate internucleotide linkage impacts oligonucleotide-enzyme interaction, and modulates siRNA activity and allele specificity.

Ken Yamada, Samuel Hildebrand, Sarah M Davis

|Aug 04, 2019

A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system.

Julia F Alterman, Bruno M D C Godinho, Matthew R Hassler

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Frequent Collaborators

6 joint publications

Anastasia Khvorova

5 joint publications

Chantal M Ferguson

5 joint publications

Julia F Alterman

4 joint publications

Bruno M D C Godinho

3 joint publications

Vignesh Narayan Hariharan

3 joint publications

Dimas Echeverria

3 joint publications

Ken Yamada

2 joint publications

Rachael Miller

2 joint publications

Qi Tang

2 joint publications

Nicholas McHugh

Frequent Collaborators

6 joint publications

Anastasia Khvorova

5 joint publications

Chantal M Ferguson

5 joint publications

Julia F Alterman

4 joint publications

Bruno M D C Godinho

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