Bruno M D C Godinho

5PUBLICATIONS
26CO-AUTHORS
Biologically active moleculesMolecular targetsMedical molecular engineering of nucleic acids and proteinsCellular nervous system
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (5)

|Aug 01, 2024
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones.

Ken Yamada, Vignesh N Hariharan, Jillian Caiazzi

|Jul 09, 2024
RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice.

Alexandra Weiss, James W Gilbert, Iris Valeria Rivera Flores

|Jul 03, 2023
Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.

Vignesh Narayan Hariharan, Jillian Caiazzi, Rachael Miller

|Oct 03, 2022
Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington's disease models.

Faith Conroy, Rachael Miller, Julia F Alterman

|Aug 04, 2019
A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system.

Julia F Alterman, Bruno M D C Godinho, Matthew R Hassler

Pageof 1