Kenichi Kusakabe
14PUBLICATIONS
8CO-AUTHORS
Get your video featured.
Publish with JoVEGet your video featured.
Publish with JoVE
Publications (14)
Sort by Publication Date:
|Mar 17, 2026
Discovery of Highly Selective HDAC2 Inhibitors in Cells That Elevate Histone Acetylation In Vivo without Adverse Effects from Dual Inhibition of HDAC1 and 2.Naoyuki Suzuki, Hidekuni Yamakawa, Ken Yoshihara
|Aug 13, 2024
Dual 5-HT2A and 5-HT2C Receptor Inverse Agonist That Affords In Vivo Antipsychotic Efficacy with Minimal hERG Inhibition for the Treatment of Dementia-Related Psychosis.Takuya Oguma, Kohei Jino, Kenji Nakahara
|Feb 16, 2023
A Quantum Mechanics-Based Method to Predict Intramolecular Hydrogen Bond Formation Reflecting P-glycoprotein Recognition.Takuya Oguma, Shota Uehara, Kenji Nakahara
|Sep 23, 2021
Discovery of Extremely Selective Fused Pyridine-Derived β-Site Amyloid Precursor Protein-Cleaving Enzyme (BACE1) Inhibitors with High In Vivo Efficacy through 10s Loop Interactions.Tatsuhiko Ueno, Eriko Matsuoka, Naoya Asada
|Sep 23, 2021
JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective BACE1 Inhibitor Targeting the S3 Pocket: From Discovery to Clinical Candidate.Frederik J R Rombouts, Ken-Ichi Kusakabe, Richard Alexander
|Mar 15, 2021
Structure-Based Approaches to Improving Selectivity through Utilizing Explicit Water Molecules: Discovery of Selective β-Secretase (BACE1) Inhibitors over BACE2.Kazuki Fujimoto, Shuhei Yoshida, Genta Tadano
Pageof 3
