Kazuya Hasegawa

11PUBLICATIONS
55CO-AUTHORS
Biologically active moleculesMedical infection agents (incl. prions)Genetic immunologyCheminformatics and quantitative structure-activity relationshipsPhotonics, optoelectronics and optical communications
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Publications (11)

|Jan 20, 2025
An orally available P1'-5-fluorinated Mpro inhibitor blocks SARS-CoV-2 replication without booster and exhibits high genetic barrier.

Nobuyo Higashi-Kuwata, Haydar Bulut, Hironori Hayashi

|Sep 05, 2024
Structural and virologic mechanism of the emergence of resistance to Mpro inhibitors in SARS-CoV-2.

Shin-Ichiro Hattori, Haydar Bulut, Hironori Hayashi

|Jul 12, 2023
GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants.

Manabu Aoki, Hiromi Aoki-Ogata, Haydar Bulut

|Feb 25, 2023
Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.

Nobuyo Higashi-Kuwata, Kohei Tsuji, Hironori Hayashi

|Feb 22, 2023
Detailed analysis of distorted retinal and its interaction with surrounding residues in the K intermediate of bacteriorhodopsin.

Shoun Taguchi, Satomi Niwa, Hoang-Anh Dao

|Jun 01, 2022
In situ crystal data-collection and ligand-screening system at SPring-8.

Hideo Okumura, Naoki Sakai, Hironori Murakami

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Frequent Collaborators

5 joint publications

Takashi Kumasaka

4 joint publications

Masaki Yamamoto

4 joint publications

Haydar Bulut

4 joint publications

Hironori Hayashi