Shin-Ichiro Hattori

9PUBLICATIONS
55CO-AUTHORS
Biomolecular modelling and designBiologically active moleculesMedical infection agents (incl. prions)Genetic immunologyCheminformatics and quantitative structure-activity relationships
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Publications (9)

|Jun 30, 2026
Design, synthesis, and X-ray structural studies of potent SARS-CoV-2 Mpro inhibitors containing tetrahydroisoquinoline-3-carboxamides as P2 ligands.

|Jan 20, 2025
An orally available P1'-5-fluorinated Mpro inhibitor blocks SARS-CoV-2 replication without booster and exhibits high genetic barrier.

Nobuyo Higashi-Kuwata, Haydar Bulut, Hironori Hayashi

|Sep 05, 2024
Structural and virologic mechanism of the emergence of resistance to Mpro inhibitors in SARS-CoV-2.

Shin-Ichiro Hattori, Haydar Bulut, Hironori Hayashi

|Jul 12, 2023
GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants.

Manabu Aoki, Hiromi Aoki-Ogata, Haydar Bulut

|Feb 25, 2023
Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.

Nobuyo Higashi-Kuwata, Kohei Tsuji, Hironori Hayashi

|May 16, 2022
Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA.2.

Ryuta Uraki, Maki Kiso, Shun Iida

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Frequent Collaborators

7 joint publications

Hiroaki Mitsuya

5 joint publications

Nobuyo Higashi-Kuwata

5 joint publications

Haydar Bulut

5 joint publications

Yoshihiro Kawaoka