Geoff S Higgins

10PUBLICATIONS

128CO-AUTHORS

Molecular targetsCancer therapy (excl. chemotherapy and radiation therapy)Cancer diagnosisPredictive and prognostic markersRadiation therapy

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Publications (10)

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|Jul 13, 2026

The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacy.

|Jun 12, 2026

<i>SHLD2</i> loss is a synthetic vulnerability to Polθ inhibition combined with radiotherapy.

|Apr 30, 2026

Structure-guided optimisation of fenofibrate-derived oxidative phosphorylation inhibitors to modify tumour hypoxia.

|Jan 24, 2025

Translation of PET radiotracers for cancer imaging: recommendations from the National Cancer Imaging Translational Accelerator (NCITA) consensus meeting.

Martina A McAteer, Daniel R McGowan, Gary J R Cook

|Sep 06, 2024

Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action.

James P B O'Connor, Victoria Tessyman, Ross A Little

|Aug 21, 2024

The Proteogenomics of Prostate Cancer Radioresistance.

Roni Haas, Gavin Frame, Shahbaz Khan

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Frequent Collaborators

Robert A Heald

Nicole Machado

Helen M R Robinson

Eeson Rajendra

Jayesh B Majithiya

Gonzalo Rodriguez-Berriguete

Marco Ranzani

Alessandro Galbiati

Graeme C M Smith

Vera Grinkevich

Frequent Collaborators

Robert A Heald

Nicole Machado

Helen M R Robinson

Eeson Rajendra