Scott D Edmondson

6PUBLICATIONS
19CO-AUTHORS
Biomolecular modelling and designCheminformatics and quantitative structure-activity relationshipsIndustrial microbiology (incl. biofeedstocks)Autoimmunity
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Publications (6)

|Nov 10, 2026
Accelerating Lead Optimization Away from Anti-Targets: Navigating the Structural Complexity of Promiscuous ADMET Proteins.

|Apr 29, 2026
Design of Cyclic Vinyl Sulfones as WRN Covalent Inhibitors from Noncovalent Binders.

|Aug 27, 2025
Knowledge and Structure-Based Drug Design of 15-PGDH Inhibitors.

Leela S Dodda, Sebastien Campos, David Ciccone

|Dec 10, 2024
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor.

Jeffrey W Johannes, Amber Y S Balazs, Derek Barratt

|Oct 08, 2024
Discovery of the First Clinical Protein Degrader for the Treatment of Autoimmune Indications: Orally Bioavailable and Selective IRAK4 Degrader KT-474.

Scott D Edmondson

|Jul 10, 2023
Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279.

Silvana Leit, Jeremy Greenwood, Samantha Carriero

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Frequent Collaborators

1 joint publications

Phani Ghanakota

1 joint publications

Jeffrey W Johannes

1 joint publications

Amber Y S Balazs

1 joint publications

Paolo Di Fruscia