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Updated: Jul 10, 2026

Evaluation of Exon Inclusion Induced by Splice Switching Antisense Oligonucleotides in SMA Patient Fibroblasts
07:02

Evaluation of Exon Inclusion Induced by Splice Switching Antisense Oligonucleotides in SMA Patient Fibroblasts

Published on: May 11, 2018

A Smadトランスクリプションコアプレッサー

D Wotton1, R S Lo, S Lee

  • 1Cell Biology Program, Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

Cell
|April 13, 1999
PubMed
まとめ

この研究は,核内のSmad2-Smad4複合体が転写を活性化したり抑制したりすることを明らかにしています. このスイッチは,彼らがコアクティベーターまたはTGIFおよびヒストン脱酸化酵素 (HDAC) を採用するかどうかに依存します.

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