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Updated: Jun 27, 2026

A GPC3-targeting Bispecific Antibody, GPC3-S-Fab, with Potent Cytotoxicity
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A GPC3-targeting Bispecific Antibody, GPC3-S-Fab, with Potent Cytotoxicity

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CD36欠乏症とインスリン抵抗性

Y Iizuka, T Gotoda, S Ishibashi

    Lancet (London, England)
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    PubMed
    まとめ

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    Last Updated: Jun 27, 2026

    A GPC3-targeting Bispecific Antibody, GPC3-S-Fab, with Potent Cytotoxicity
    11:13

    A GPC3-targeting Bispecific Antibody, GPC3-S-Fab, with Potent Cytotoxicity

    Published on: July 12, 2018

    A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants
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    A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants

    Published on: August 9, 2019

    Adoptive Immunotherapy of iNKT Cells in Glucose-6-Phosphate Isomerase (G6PI)-Induced RA Mice
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    Receptor Downregulation in MVBs

    Multivesicular bodies (MVBs) are mature endosomes that sort ubiquitinated proteins and then fuse with lysosomes to degrade the sorted proteins. Epidermal growth factor (EGF) and its receptor (EGFR) form a complex that can be internalized through endocytosis, sorted into an MVB, and later degraded.
    The EGFR can initiate signaling pathways that  lead to cell proliferation, migration, and differentiation. Overexpression of EGFR  stimulates cells to proliferate. Excessive  EGFR activation may...

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