TUFは"ゴミ"DNAに対する愛
Aarron T Willingham1, Thomas R Gingeras
1Affymetrix, Inc., Santa Clara, CA 95051, USA.
Cell
|July 4, 2006
まとめ
非コーディングRNA (ncRNA) は,真核生物に豊富に存在し,ゲノム組織と調節において重要な役割を果たします. これらの機能トランスクリプトの研究は,複雑なゲノムプロセスを理解するために不可欠です.
科学分野:
- ゲノミクスゲノミクスとは
- 分子生物学は分子生物学である.
- バイオインフォマティックス
背景:
- ユカリオットのゲノムには膨大な数のトランスクリプトが含まれています.
- これらのトランスクリプトの多くは,タンパク質をコードする潜在能力が欠如しており,伝統的にノンコーディングRNA (ncRNA) と呼ばれる.
- ncRNAの機能的意義は歴史的に過小評価されてきた.
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