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Updated: Feb 18, 2026

A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication
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アレカナッツで活性化されたフィブロブラストにおける代謝再プログラムとGM-CSF分泌は,口腔前がんの進行を促す

Yen-Yun Wang1,2,3, Chang-Wei Su1,4, Chih-Huang Tseng1,5

  • 1School of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

Oral diseases
|February 17, 2026
PubMed
まとめ

アレカナッツ抽出物 (ANE) は,線維芽細胞を活性化し,上皮からメゼンキマへの移行を増加させ,前がん細胞における上皮成長因子受容体 (EGFR) 信号伝達を強化することにより,口腔がんを促進します.

キーワード:
アレカ (Areca) とはカルチノゲネシス (がん発生)サイトカイン (cytokine) とはエピテリアからメゼンキマへの移行口腔の癌前および癌の病変に起因する.腫瘍のマイクロ環境

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