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Updated: May 5, 2026

A Modified Yeast-one Hybrid System for Heteromeric Protein Complex-DNA Interaction Studies
10:47

A Modified Yeast-one Hybrid System for Heteromeric Protein Complex-DNA Interaction Studies

Published on: July 24, 2017

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酵母和人类的TFIID具有改变了TATA元素的DNA结合特异性

M Strubin1, K Struhl

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115.

Cell
|February 21, 1992
PubMed
概括

研究人员设计了一种酵母TFIID蛋白来识别突变的TATA元素,这对于RNA聚合酶II转录至关重要. 这种修改还使人类TFIID能够在酵母中发挥作用,揭示了基因调节中的关键相互作用.

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