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Updated: Jul 23, 2025

Genome-wide Mapping of Protein-DNA Interactions with ChEC-seq in Saccharomyces cerevisiae
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与SpLiT-ChEC同时绘制DNA结合和核细胞定位的地图.

Orion G B Banks1, Michael J Harms1,2, Jeffrey N McKnight1,3

  • 1Institute of Molecular Biology, University of Oregon, Eugene OR 97403, USA.

bioRxiv : the preprint server for biology
|July 18, 2023
PubMed
概括

研究人员开发了SpyCatcher Endogenous Cleavage的链接准 (SpLiT-ChEC),以同时绘制蛋白质-DNA相互作用和核细胞定位的地图. 这种新的方法为研究染色体组织提供了精确的时间控制.

关键词:
染色体组织组织 染色体组织核酶体定位定位是如何进行的转录因子结合的转录因子

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Chromatin immunoprecipitation, or ChIP, is an antibody-based technique used to identify sites on DNA that bind to transcription factors of interest or histone proteins. It also helps determine the type of histone modifications such as acetylation, phosphorylation, or methylation.
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