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Updated: Jul 21, 2025

Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C
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从二维染色体构造捕获数据中重建3D基因组结构的技术和挑战

Zilong Li1, Stephanie Portillo-Ledesma1, Tamar Schlick2

  • 1Department of Chemistry, New York University, 100 Washington Square East, Silver Building, New York, 10003, NY, USA; Simons Center for Computational Physical Chemistry, New York University, 24 Waverly Place, Silver Building, New York, NY, 10003, USA.

Current opinion in cell biology
|July 28, 2023
PubMed
概括

计算方法从二维接触数据中重建3D染色质结构,提供对基因组折叠和调节的生物学见解. 这种方法有助于理解基因组织和机制.

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