在normosmic个体的嗅觉训练:一个随机对照试验.
I T Heian1, W M Thorstensen2, T A Myklebust3
1Institute of Neuromedicine and Movement Science (INB), Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Department of Otolaryngology, Head and Neck Surgery, Molde Sjukehus, Helse More Romsdal, Molde, Norway; Department of Research and Innovation, Helse More and Romsdal, Norway.
Rhinology
|October 17, 2023
概括
嗅觉训练 (OT) 对具有正常嗅觉的个体对嗅觉功能的影响有限. 较短的训练课程似乎可以提高服从度,而长时间的嗅觉训练没有被证明的好处.
科学领域:
- 神经科学是一个神经科学.
- 感官科学 感官科学
背景情况:
- 嗅觉训练 (OT) 是为嗅觉功能障碍而建立的.
- 它对诺莫斯米亚 (正常的嗅觉) 患者的影响尚不确定.
研究的目的:
- 研究不同暴露时间的OT对正常个体的嗅觉功能的影响.
- 为了比较标准的OT (40秒) 与延长的OT (4分钟) 每天三个月.
主要方法:
- 一个随机对照试验,涉及200名参与者.
- 干预组在三个月内每天两次使用四种气味进行了OT.
- 使用Sniffin Sticks测试在基线,干预后和一年后跟踪评估的嗅觉功能.
主要成果:
- 在干预后或随访时,在OT组中都没有观察到嗅觉功能的显著改善.
- 在基线因素 (性别,年龄,过敏,教育) 和嗅觉功能的变化之间没有发现相关性.
- 扩展的OT组报告说,训练次数显著减少,这表明服从程度较低.
结论:
- 嗅觉训练对诺莫斯米亚患者的嗅觉功能的影响有限.
- 延长OT持续时间并不比标准OT提供优越的好处.
- 较短的培训时间可能会提高对嗅觉培训计划的坚持.
相关概念视频
Olfaction
44.4K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
The olfactory receptors are embedded in the cilia of the...
44.4K
Olfactory Receptors: Location and Structure
9.3K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
9.3K
Physiology of Smell and Olfactory Pathway
8.6K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
The olfactory...
8.6K


