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Updated: Jun 29, 2025

In Vivo Detection and Analysis of Rb Protein SUMOylation in Human Cells
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USP7与SET上蛋白相互作用并使其不稳定

Jianyuan Chen1, Zishan Jiao1, Yajing Liu1

  • 1State Key Laboratory of Common Mechanism Research for Major Diseases & Department of Medical Genetics, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, China.

Biochemical and biophysical research communications
|March 31, 2024
PubMed
概括

这项研究确定了泛素特异性蛋白酶7 (USP7) 作为蛋白SE转位 (SET) 的调节者. USP7 破坏了 SET 蛋白水平的稳定性,为癌症治疗提供了一个新的目标.

关键词:
蛋白质与蛋白质的相互作用设置 设置 设置稳定化 稳定化 稳定化两者并排的亲和力净化.USP7 USP7 美国

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