OPTN/SRTR 2023 年度数据报告:心脏
Monica M Colvin1, Jodi M Smith2, Yoon Son Ahn3
1Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN; Department of Cardiology, University of Michigan, Ann Arbor, MI.
概括
2018年成人心脏移植政策的修订对心脏移植产生了积极的影响,增加了心脏移植率,并减少了等候名单上的死亡. 尽管存在挑战,但它有利于高急性患者,并显示多器官移植的良好结果.
科学领域:
- 心脏病学 心脏病学
- 移植手术 移植手术
- 公共卫生政策 公共卫生政策
背景情况:
- 2018年成人心脏移植政策的修订旨在改善器官分配和患者的治疗结果.
- 在政策实施后,心脏移植数量显著增加,捐赠者患病率发生变化.
研究的目的:
- 评估2018年成人心脏移植政策修订对移植率,等待名单死亡率和患者敏度的影响.
- 分析成人和儿科心脏移植的趋势,包括多器官移植和特定患者群体的结果.
主要方法:
- 对2012年至2023年全国心脏移植数据的分析.
- 移植率,等待名单死亡率和移植后生存率在2018年政策修订之前和之后的比较.
- 检查不同患者急性,诊断 (包括先天性心脏病) 和多器官移植接受者的结果.
主要成果:
- 成年人心脏移植的数量显著增加,到2023年达到创纪录的4092例,这得益于2018年政策的有利影响.
- 成年人等候名单死亡率在2023年达到每100个患者年8.5例死亡的低点;较高敏度的患者更快地接受了移植.
- 儿童心脏移植率下降,导致等待时间更长,尽管急诊列表增加.
结论:
- 2018年成人心脏移植政策的修订成功地提高了移植率,降低了等候名单死亡率,特别是在高急性患者中.
- 虽然成年人的结果是有利的,但患有先天性心脏病的成年人需要进一步的研究,以改善移植后的生存率.
- 儿科心脏移植面临的挑战是移植率下降和等待时间增加,需要对政策进行审查.
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