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使用人工智能驱动的药物设计平台识别一种新型的Indolizine RORγT反向激素

Rafał A Bachorz1, Joanna Pastwińska2, Michael S Lawless1

  • 1Simulations Plus, Inc., P.O. Box 12317, Research Triangle Park, North Carolina 27709, United States.

ACS medicinal chemistry letters
|July 16, 2025
PubMed
概括

使用人工智能驱动药物设计 (AIDD) 的自动化多参数优化 (MPO) 创建了新的 RORγT 联体. 许多化合物表现出RORγT抑制和有利的ADMET特性,其中一种有力的化合物显示出治疗潜力.

关键词:
罗格特 (Rorgt) 的意思是说.人工智能的人工智能是人工智能.药物设计 药物设计反向激动剂的反向激动剂.

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