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Updated: Jan 10, 2026

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
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Pacs1-Wdr37复杂组装和稳定性的结构基础

Le Xiao, Magdalena Grzemska, Xiong Pi

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    Pacs1-Wdr37复杂结构揭示了Pacs1如何结合Wdr37,这对蛋白质稳定至关重要. Pacs1 中的神经发育突变不会破坏这个复合体,但可以提供治疗点.

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