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Updated: Feb 11, 2026

Kinetic Screening of Nuclease Activity using Nucleic Acid Probes
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在临床前核酸治疗学研究中的模型选择

Peter L Oliver1, Alyssa C Hill2

  • 1MRC Nucleic Acid Therapy Accelerator (NATA), Research Complex at Harwell, Harwell Science and Innovation Campus, Oxford, UK. p.oliver@har.mrc.ac.uk.

Communications biology
|February 9, 2026
PubMed
概括

选择有效的临床前模型对于推进抗意义寡核酸 (ASOs) 和小干扰RNA (siRNAs) 等核酸疗法 (NATs) 来说至关重要,从实验室研究到临床使用.

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