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[The effect of shear stress on vascular endothelium]
1Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, Kiev.
Fiziolohichnyi Zhurnal (Kiev, Ukraine : 1994)
|December 8, 1998
Abstract:
Effects of shear stress on intracellular Ca2+ concentration ([Ca2+]i) and membrane potential of intact endothelium of the rat aorta have been investigated. Shear stress and acethylcholine both evoked endothelium-dependent relaxation of the rat aorta, but in contrast to acethylcholine shear stress did not affect [Ca2+]i and membrane potential of the endothelium. These data do not corroborate the hypotheses on involvement of Ca2+ and membrane potential in reception of shear stress by endothelium.