Related Experiment Videos

The measurement of efficacy in the drug discovery agonist selection process

¹Department of Receptor Biochemistry, Glaxo Wellcome Research and Development, 5 Moore Drive, Research Triangle Park, NC 27709, USA. tpk1348@glaxo.com

Journal of Pharmacological and Toxicological Methods

|October 18, 2000

Abstract

No abstract available in PubMed .

Related Concept Videos

Articles linked to this work by shared authors, journal, and citation graph.

The tail wags the dog: possible mechanism for reverse allosteric control of ligand-activated channels.

British journal of pharmacology·2013

What systems can and can't do.

British journal of pharmacology·2008

The relative importance of the time-course of receptor occupancy and response decay on apparent antagonist potency in dynamic assays.

Journal of autonomic pharmacology·2001

Inverse, protean, and ligand-selective agonism: matters of receptor conformation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2001

The use of stimulus-biased assay systems to detect agonist-specific receptor active states: implications for the trafficking of receptor stimulus by agonists.

Molecular pharmacology·2000

Pharmacological characterization of receptor-activity-modifying proteins (RAMPs) and the human calcitonin receptor.

Journal of pharmacological and toxicological methods·2000

See all related articles