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Published on: March 13, 2018
Acute parotitis due to dengue virus
J R Torres1, F Liprandi, A P Goncalvez
1Instituto de Medicina Tropical, Universidad Central de Venezuela, Caracas, Venezuela. torresj@camelot.rect.ucv.ve.
Summary
Acute bilateral parotitis, or salivary gland swelling, can signal various health issues. This case highlights dengue fever as a rare cause, with dengue virus detected in saliva for the first time.
Area of Science:
- Infectious Diseases
- Virology
- Immunology
Background:
- Acute bilateral parotitis is a recognized clinical manifestation across diverse conditions, including infections, autoimmune disorders, metabolic disturbances, and drug reactions.
- The parotid glands, the largest salivary glands, can become inflamed and enlarged due to various systemic and local factors.
Observation:
- A unique case of bilateral parotitis was observed in an immunocompetent individual diagnosed with dengue fever.
- The patient presented with symmetrical swelling and inflammation of both parotid glands.
Findings:
- This study provides the first documented evidence of dengue virus presence in the saliva of a patient with dengue fever-associated parotitis.
- Laboratory confirmation of dengue virus infection was established.
Implications:
- This finding expands the differential diagnosis for acute bilateral parotitis to include dengue fever, particularly in endemic regions.
- The detection of dengue virus in saliva suggests potential salivary transmission routes, warranting further investigation.
- Highlights the importance of considering viral etiologies in parotitis cases, even in immunocompetent patients.
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