[Ultrastructural pathologic research on the adult laryngeal papilloma]

In this paper, the ultrastructural features of laryngeal papillomas of 9 cases of adult patients were investigated by means of SEM. It showed that the polypoid surface of the papilloma is easily recognized; the surface cells are covered by microvilli of different size and shape; and the epithelium is bordered by an irregular and continuous basement membrane. In some areas, there is pseudopodium of basal cells stretching into connective tissue. The structure of interface between basement membrane and connective tissue varies with aggravation of tumor cell atypia. The significant variation of structural of basement membrane and semidesmosomes suggests the possibility of malignant change.