Related Experiment Video
Updated: Aug 2, 2026

07:57
A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Depression and service utilization in elderly primary care patients
M P Luber1, B S Meyers, P G Williams-Russo
1Department of Psychiatry, University of Pennsylvania, USA.
Summary
Elderly patients diagnosed with depression utilized more healthcare services, including more appointments and tests. This increased utilization was linked to nonspecific medical complaints, suggesting depression
Area of Science:
- Geriatrics
- Primary Care Medicine
- Mental Health Services Research
Background:
- Depression is prevalent in elderly primary care patients.
- The impact of depression diagnosis on healthcare resource utilization in this population is not fully understood.
- Somatic symptoms are common presentations of depression in older adults.
Purpose of the Study:
- To examine the association between a depression diagnosis and health services utilization in elderly primary care patients.
- To investigate the relationship between nonspecific medical complaints, depression, and healthcare costs.
Main Methods:
- Retrospective analysis of health services utilization data.
- Study included 3,481 elderly patients over 12 months in a primary care setting.
- Statistical analysis controlled for patient comorbidity.
Main Results:
- Depressed elderly patients had significantly higher outpatient resource utilization (appointments, tests, consultations) compared to non-depressed patients.
- This association persisted after controlling for comorbidities.
- Nonspecific medical complaints in depressed patients were associated with increased ambulatory costs.
Conclusions:
- A depression diagnosis in elderly primary care patients is associated with increased healthcare services utilization.
- The somatic presentation of depression may drive increased healthcare resource use and costs.
- Primary care interventions addressing depression and its somatic symptoms could potentially reduce healthcare utilization.
Related Concept Videos
Drug Dosing: Geriatric Patients
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism
Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
Pharmacodynamics in Geriatric Patients: Effects of Age
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Depressive Disorders: MDD and Dysthymia
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Depressive Disorders: Etiology
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

