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[Ovarian function in androgenized rats in puberty]
1Ukrainian Research Institute of Endocrine Diseases Pharmacotherapy.
Fiziolohichnyi Zhurnal (Kiev, Ukraine : 1994)
|June 8, 2001
Abstract:
In experiment on rats injected with aromatase inhibitor or with dihydrotestosterone (DHT) it has been revealed that increase of androgens level in blood stimulates ovarial folliculogenesis on its early stages. DHT as compared with testosterone accelerates small follicles growth more effectively. Androgens, particularly DHT (7 mkg/100 g), suppress preovarial follicules maturing and turn them into atretic ones. Suppressing of ovarial functional activity delays or blockages the first ovulation during rats puberty.