Torsades de pointes caused by Mibefradil.

S Gläser1, M Steinbach, C Opitz

  • 1Unfallkrankenhaus Berlin, Department of Internal Medicine, Warener Strasse 7, D-12683 Berlin, Germany.

Summary

Mibefradil can cause dangerous heart rhythm problems, specifically Torsades de pointes, by prolonging the QTc interval. Discontinuing the drug resolved these life-threatening ventricular dysrhythmias.

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