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Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
Current use of bone substitutes in maxillofacial surgery
S Govindaraj1, P D Costantino, C D Friedman
1Department of Otolaryngology, Mt. Sinai Medical Center, 1 Gustav L. Levy Place #1189, New York, NY 10029-6574, USA.
Abstract:
The use of bone substitutes in the field of facial plastic and reconstructive surgery is well established. Because of the complexity of the anatomy in the head and neck region, reconstruction and augmentation of this area pose a challenge to the surgeon. In addition, the shortcomings of autogenous bone, such as resorption and donor site morbidity, have led to the need for alloplastic implants in the field of facial plastic surgery. Multiple alloplastic implants are currently in use today; however, those compounds that contain calcium, silicon, and carbon have been examined more closely in this article. This is because of their ability to osseointegrate and osseoconduct with surrounding fibro-osseous tissue, as well as demonstrate a higher immunogenic tolerance by the human body. The discussion of each compound includes a description of its composition and structure, the advantages and shortcomings of the material, and its current uses in the field of facial plastic and reconstructive surgery. With a better understanding of the available alloplastic implants, the surgeon can make a more informed decision as to which implant would be most suitable in a particular patient.
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