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Updated: Jul 24, 2026
08:41
Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
Current use of bone substitutes in maxillofacial surgery
S Govindaraj1, P D Costantino, C D Friedman
1Department of Otolaryngology, Mt. Sinai Medical Center, 1 Gustav L. Levy Place #1189, New York, NY 10029-6574, USA.
Facial Plastic Surgery : FPS
|January 31, 2002
Summary
Alloplastic implants, particularly those containing calcium, silicon, and carbon, offer advantages over autogenous bone for facial plastic surgery. These materials promote osseointegration and have higher immunogenic tolerance, aiding complex reconstructions.
Area of Science:
- Biomaterials Science
- Surgical Innovation
- Craniofacial Surgery
Background:
- Facial plastic and reconstructive surgery faces challenges due to complex head and neck anatomy.
- Autogenous bone grafts have limitations, including resorption and donor site morbidity.
- The need for reliable bone substitutes in facial augmentation and reconstruction is critical.
Purpose of the Study:
- To review alloplastic bone substitutes for facial plastic and reconstructive surgery.
- To focus on calcium, silicon, and carbon-containing compounds due to their favorable properties.
- To provide surgeons with information for informed implant selection.
Main Methods:
- Literature review of alloplastic bone substitute compounds.
- Analysis of materials containing calcium, silicon, and carbon.
- Evaluation of osseointegration, osseoconduction, and immunogenic tolerance.
- Discussion of composition, structure, advantages, shortcomings, and current uses.
Main Results:
- Alloplastic implants offer an alternative to autogenous bone in facial surgery.
- Calcium, silicon, and carbon-based compounds exhibit excellent osseointegration and osseoconduction.
- These materials demonstrate high immunogenic tolerance, reducing adverse reactions.
- Specific compounds have demonstrated efficacy in various reconstructive and augmentation procedures.
Conclusions:
- Alloplastic implants, especially those with calcium, silicon, and carbon, are valuable in facial plastic and reconstructive surgery.
- Their ability to osseointegrate and their biocompatibility make them superior to autogenous bone in many cases.
- Understanding material properties aids surgeons in selecting optimal implants for patient-specific needs.
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