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Interpretation and classification of microvolt T wave alternans tests.
Daniel M Bloomfield1, Stefan H Hohnloser, Richard J Cohen
1Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA. dmb9@columbia.edu
Journal of Cardiovascular Electrophysiology
|May 28, 2002
Summary
Microvolt T wave alternans (TWA) measurement during exercise stress tests is now feasible. This new technology shows promise as a strong predictor of arrhythmia risk across various conditions, guiding clinical interpretation.
Area of Science:
- Cardiology
- Electrophysiology
- Biomedical Engineering
Background:
- Sophisticated noise reduction and analytic methods enable microvolt T wave alternans (TWA) measurement during exercise stress testing.
- Microvolt TWA is emerging as a significant predictor of arrhythmia risk in patients with diverse underlying conditions.
Purpose of the Study:
- To establish uniform standards for the clinical interpretation of microvolt T wave alternans (TWA) tracings.
- To guide physicians in interpreting new TWA data from exercise stress tests.
Main Methods:
- Review of current technologies for microvolt T wave alternans (TWA) measurement.
- Analysis of existing data on TWA as a predictor of arrhythmia risk.
Main Results:
- Microvolt TWA measurement is now clinically feasible during routine exercise stress testing.
- Available data indicate microvolt TWA is a potent predictor of arrhythmia risk.
Conclusions:
- Physicians will increasingly encounter microvolt TWA data.
- Standardized interpretation guidelines are necessary for this emerging technology.