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Published on: July 5, 2021
Sinus node dysfunction associated with lithium therapy in a child
Jose Manuel Moltedo1, George A Porter, Mathew W State
1Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Insights
Lithium is a common psychiatric treatment. This case study highlights potential cardiac side effects in children, a risk previously undocumented in pediatric patients receiving lithium therapy.
Area of Science:
- Pediatric Cardiology
- Psychiatric Pharmacology
Background:
- Lithium salts are widely prescribed for psychiatric conditions in adults and children, including bipolar disorder.
- Cardiac side effects of lithium are well-documented in adult populations.
Observation:
- A 9-year-old boy on long-term lithium therapy presented with cardiac toxicity.
- This case represents a rare instance of lithium-induced cardiac issues in a pediatric patient.
Findings:
- The patient experienced adverse cardiac events during lithium treatment.
- This case underscores the potential for cardiac toxicity in children receiving lithium.
Implications:
- Clinicians should be vigilant for cardiac side effects in pediatric patients undergoing lithium therapy.
- Further research is warranted to understand and monitor lithium's cardiac impact in children.
Abstract:
Lithium salts have been used extensively in both adults and children during the last 30 years, for the treatment of a variety of psychiatric conditions, including bipolar disorder The cardiac side effects of lithium in adult patients have been well described. However, to the best of our knowledge, there are no reports of lithium-induced cardiac side effects in pediatric patients. We describe the case of a 9-year-old boy who developed cardiac toxicity while receiving long-term lithium therapy.
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