[Evaluation on hemorrhage factors secondary to endoscopic sinus surgery with multiple stepwise regression analysis]

To investigate the factors relating to bleeding secondary to endoscopic sinus surgery.

193 patients suffered from nasal polyps, chronic sinusitis and underwent endoscopic sinus surgery between May 1995 and February 2001 were analyzed. These patients's state of operation affairs tallies with this study's selecting condition and their clinic data was complete. The factors relating to bleeding secondary to endoscopic sinus surgery were analyzed with multiple stepwise regression analysis with STATA31 statistic computer software.

20 selected hemorrhage factors were analyzed with multiple stepwise regressions. With these factors progressively removed, 5 items as follows showed relation to the hemorrhage: X18, X19, X9, X11, X20. An optimal regression equation for predicting hemorrhage has been established. According to this equation, the blood loss of endoscopic sinus surgery could be estimated.

The clinical signification of 5 factors were recognized: 1. X18: Anatomy mark was broken down in former operation and showed difficulty when identified. 2. X19: Sinus presented proliferation such as scar forming, blood vessel showed hyperemia, sinus wall showed hyperplasia, Aperture being narrow and small. 3. X9: Sinusitis showed late stages. 4. X11: Estimated blood loss was significantly greater under general anesthesia. 5. X20: Operation went on over 2 hours. If aforementioned condition appears, blood loss may exceed 200 ml.