Related Experiment Video
Updated: Aug 2, 2026
Whole Mount Dissection and Immunofluorescence of the Adult Mouse Cochlea
Published on: January 1, 2016
[Local microcirculatory disorders in the cochlea basal turn near termination in guinea pigs]
1Department of Otolaryngology, Southwest Hospital, Third Military Medical University, Chongqing 400038.
Objective:
To study the characteristics of hearing loss caused by local microcirculatory disorders in the cochlea basal turn near termination of guinea pigs.
Method:
The local microcirculatory disorders in the cochlea basal turn near termination of guinea pigs were caused by photochemical reaction; morphological changes were observed by light microscope; the CAP N1 amplitude, CAP N1 latency and CAP N1 threshold shift which were evoked by short tone burst were recorded by Madsen 2250.
Result:
Morphological changes showed that histopathological changes were located in the basal turn near termination of cochlea. The CAP N1 amplitude, CAP N1 latency and CAP N1 threshold shift showed that the hearing loss was remarkable in the high-range frequencies.
Conclusion:
If the local microcirculatory disorders in the cochlea basal turn near termination take place, the hearing losses are more remarkable in the high-range frequencies.
