[Epstein-Barr virus and Hodgkin's lymphoma]
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Updated: Sep 27, 2026

An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection
Published on: March 30, 2018
Henrik Hjalgrim1, Lars Munksgaard, Mads Melbye
1Afdeling for Epidemiologisk Forskning, Statens Serum Institut, DK-2300 København S. hhj@ssi.dk
Abstract:
The suspicion that Hodgkin's lymphoma, previously known as Hodgkin's disease, may have an infectious etiology has existed for many years. The assumption rests on epidemiological characteristics, in particular a strong correlation between socio-economic status and risk of Hodgkin's lymphoma in young adults, as well as both serological and molecular biological evidence that the Epstein-Barr virus is involved in the development of up to 50% of all cases of Hodgkin's lymphoma. We present the current epidemiological, serological and molecular biological evidence for an infectious etiology to Hodgkin's lymphoma with emphasis on the association with Epstein-Barr virus.
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