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[Study on the relationship between microvascular density and prognosis in laryngeal cancer]
1Department of Otorhinolaryngology, First Affiliated Hospital, College of Medical Sciences, Zhejiang University, Hangzhou 310003.
Lin Chuang Er Bi Yan Hou Ke Za Zhi = Journal of Clinical Otorhinolaryngology
|February 5, 2003
Abstract
Objective:
To study the relationship between the microvascular density(MVD) and the prognosis in laryngeal cancer.
Method:
Microvessel quantitation in 31 cases of laryngeal cancer was done with factor VIII-related antibody and SABC method.
Result:
The quantitation of microvessels in laryngeal cancer were negative of histologic grade and type, but were significantly different (P < 0.05) between metastasis (10.23 +/- 0.78) and without metastasis(6.38 +/- 0.33) two years after operation.
Conclusion:
The angiogenesis of laryngeal cancer is correlated with the lymph node metastasis and prognosis.