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New potentialities of HPLC in pharmacopoeian analysis
G I Baram1, D V Reihart, E D Gol'dberg
1Limnological Institute, Siberian Division of Russian Academy of Sciences, Irkutsk.
Bulletin of Experimental Biology and Medicine
|April 30, 2003
Abstract:
Modern status of pharmacopoeian HPLC analysis and its main shortcomings are discussed. The philosophy "special analytical method for each substance" has to be revised, and as an alternative, a principle of creation of universal methods realized by means of HPLC analyzers is proposed. A prototype of such analyzer is described. The device was designed on the basis of a Milichrome A-02 gradient chromatograph with spectrophotometric detector and reverse phase column.