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Polarized Translocation of Fluorescent Proteins in Xenopus Ectoderm in Response to Wnt Signaling
Published on: May 26, 2011
[Distribution of the Xvent-2 mRNA between informosomes and polysomes in early frog development]
A S Voronina1, E S Pshennikova, D V Shatilov
1Bakh Institute of Biochemistry, Russian Academy of Sciences, Moscow, 119071 Russia. voronina@inbi.ras.ru
Abstract:
Translational expression regulation was studied for Xvent-2 coding for a transcription factor involved in dorsoventral differentiation of amphibian embryos. The Xvent-2 mRNA was detected predominantly in informosomes at all developmental stages examined, and only its minor fraction was associated with polysomes. Expression of Xvent-2 was assumed to be regulated at the translational level, with Xvent-2 produced immediately before polypotent cells enter a certain differentiation pathway.

