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Updated: Aug 10, 2026
10:28
Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice
Published on: February 18, 2016
[Cocaine and opiate related disorders]
R Stohler1, K M Dürsteler-MacFarland
1Psychiatrische Universitätsklinik Zürich West, Zürich.
Therapeutische Umschau. Revue Therapeutique
|July 10, 2003
Summary
This study examines the evolution of addiction treatment, contrasting abstinence, psychotherapy, and metabolic theories. It recommends a multimodal, integrated approach for modern substance use patterns.
Area of Science:
- Addiction research
- Neuroscience
- Psychiatry
Context:
- Historical evolution of addiction conceptualization over three centuries.
- Emerging trends in substance use, including speed-balling, chasing, and multi-substance use in Europe.
- Critique of traditional treatment modalities: prohibitionist (abstinence), defect theory (psychotherapy).
Purpose:
- To review the historical development of addiction theories and treatments.
- To present newer treatment modalities in response to evolving consumption patterns.
- To advocate for a comprehensive, individualized addiction treatment strategy.
Summary:
- Presents the historical progression of understanding addiction, from early concepts to modern theories.
- Discusses contrasting treatment philosophies: abstinence, psychotherapeutic defect models, and the Metabolic Theory.
- Highlights contemporary substance use trends and introduces emerging treatment approaches.
- Recommends a multimodal, integrated, and individualized treatment model for addiction.
Impact:
- Informs the development of more effective and personalized addiction treatment strategies.
- Provides a framework for understanding the complexities of addiction and its management.
- Contributes to the scientific discourse on substance use disorders and their therapeutic interventions.
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