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Published on: October 19, 2014
[CT characters of primary nasal non-Hodgkin lymphoma]
Kaiming Su1, Jiejie Xu, Mingzhe Qiao
1Department of Otolaryngology, No. 81st, Hospital of PLA, Nanjing 210029.
Objective:
To analyze the computed tomography (CT) characters of primary nasal non-Hodgkin lymphoma (NHL) with histologic phenotype.
Method:
The CT data of 21 patients who were diagnosed as primary nasal NHL from 1994 to 2002 were analyzed retrospectively in which 16 cases have T-cell subtype, 2 with B-cell and 3 with T/NK-cell subtype in immunohistochemical examination. CT literatures were also evaluated in 40 patients with nasal polyp and 18 patients with non-NHL malignant tumor simultaneously as comparison groups.
Result:
Soft tissue mass and hypertrophic mucosa were the main CT finding in nasal NHL, neoplasms may be found growing in expanding manner like benign tumor (P < 0.01). Contrast to nasal polyp and other nasal malignant tumor, hypertrophic mucosa located on the front of nasal septum can be more frequently viewed (P < 0.01), thicken skin in nasal vestibule were only be found in NHL group. T-cell and B-cell region NHL have similar manifestations while T-NK cell region have more invasive erosion.
Conclusion:
CT images in primary nasal non-Hodgkin lymphoma have some typical characters, and may be correlated with the histologic phenotype.
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