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[Guanethidine blockade for palliative treatment in reflex dystrophy].
1Aalborg Sygehus, Anaestesiologisk-intensiv afdeling.
Ugeskrift for Laeger
|May 18, 1992
Summary
Guanethidine blockade effectively relieved pain in 68% of patients with upper limb reflex sympathetic dystrophy. Adding lignocaine to the guanethidine injection reduced procedural pain.
Area of Science:
- Pain Management
- Neurology
- Pharmacology
Context:
- Causalgia, hyperpathia, and reflex sympathetic dystrophy are debilitating conditions affecting the upper limb.
- Regional intravenous administration is a common route for certain nerve blocks.
Purpose:
- To evaluate the efficacy of guanethidine blockade in managing upper limb complex regional pain syndrome.
- To assess the impact of lignocaine on patient comfort during the procedure.
Summary:
- Twenty-two patients with upper limb causalgia, hyperpathia, and reflex dystrophy underwent guanethidine blockade.
- The regional intravenous technique involved 20 mg guanethidine, 400 IU heparin, and 70 mg lignocaine, inducing a 20-minute avascular period.
- A significant 68% of patients experienced pain relief or considerable improvement.
Impact:
- Guanethidine blockade offers a viable therapeutic option for complex regional pain syndrome in the upper limb.
- The co-administration of lignocaine enhances patient tolerance by reducing blockade-associated pain.